● I-Oncology
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I-Methylated yomntu NDRG4/SEPT9/SFRP2/BMP3/SDC2 Gene
Ikiti ihloselwe ukufunyanwa kwe-in vitro qualitative ye-methylated NDRG4 / SEPT9 / SFRP2 / BMP3 / SDC2 izakhi zofuzo kwiiseli ze-intestinal exfoliated kwiisampuli zesitulo somntu.
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Human BRAF Gene V600E Ukuguqulwa
Le khithi yovavanyo isetyenziselwa ukukhangela ngokomgangatho ukuguqulwa kofuzo lwe-BRAF ye-V600E kwiisampulu zeparafini ezifakwe kwi-melanoma yomntu, umhlaza we-colorectal, umhlaza wedlala kunye nomhlaza wemiphunga kwi-vitro.
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I-BCR-ABL ye-Fusion yoGuquko lweGene yoMntu
Le khithi ifanelekile ukufunyaniswa okusemgangathweni kwe-p190, i-p210 kunye ne-p230 isoforms ye-BCR-ABL yofuzo lwemfuza kwiisampulu zomongo womntu.
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KRAS 8 Utshintsho
Le khithi yenzelwe ukufumanisa umgangatho we-in vitro we-8 utshintsho kwi-codons 12 kunye ne-13 ye-K-ras gene kwi-DNA ekhutshiweyo kumacandelo e-pathological yabantu afakwe kwiparafini.
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Human EGFR Gene 29 Utshintsho
Le khithi isetyenziselwa kwi-vitro ngokusemgangathweni ukufumanisa utshintsho oluqhelekileyo kwi-exons 18-21 yejini ye-EGFR kwiisampulu ezivela kwizigulane ezinomhlaza wemiphunga yeseli yabantu engeyincinane.
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I-ROS1 yeFusion yoGuquko lweGene yoMntu
Le khithi isetyenziselwa ukufumanisa umgangatho we-in vitro weentlobo ezili-14 ze-ROS1 yokuguqulwa kofuzo lwe-fusion kwiisampulu zomhlaza wemiphunga yeseli yabantu engeyincinci (Itheyibhile 1).Iziphumo zovavanyo zezereferensi yeklinikhi kuphela kwaye akufanele zisetyenziswe njengesiseko sodwa sonyango lwezigulane.
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Umntu EML4-ALK Fusion Gene Mutation
Le khithi isetyenziselwa ukubona ngokusemgangathweni iintlobo ezili-12 zoguqulo lwe-EML4-ALK yofuzo lwemfuza kwiisampulu zezigulane zomhlaza wemiphunga weseli yabantu ezingancinci kwi-vitro.Iziphumo zovavanyo zezereferensi yeklinikhi kuphela kwaye akufanele zisetyenziswe njengesiseko sodwa sonyango lwezigulane.Oogqirha kufuneka benze izigwebo ezibanzi kwiziphumo zovavanyo ngokusekelwe kwizinto ezifana nemeko yesigulane, izibonakaliso zamachiza, impendulo yonyango, kunye nezinye izikhombisi zovavanyo lwebhubhoratri.
