Umxholo weWorld Malaria Day 2023 uthi "End Malaria for Good", kugxininise ekukhawuleziseni inkqubela phambili kwinjongo yehlabathi yokuphelisa isifo seengcongconi ngo-2030. Oku kuya kufuna iinzame ezizinzileyo zokwandisa ukufikelela kuthintelo lwemalariya, ukuxilongwa, kunye nonyango, ngokunjalo. njengophando oluqhubekayo kunye nezinto ezintsha zokuphuhlisa izixhobo ezintsha kunye nezicwangciso zokulwa nesifo.
01 Isishwankathelo seIsifo seengcongconi
Ngokwengxelo yeWorld Health Organisation, malunga nama-40% abantu behlabathi basengozini yesifo seengcongconi.Nyaka ngamnye, abantu abazizigidi ezingama-350 ukusa kuma-500 bosulelwa sisifo seengcongconi, abasisi-1,1 sesigidi babulawa sisifo seengcongconi, yaye abantwana abangama-3 000 babulawa sisifo seengcongconi suku ngalunye.Isiganeko sigxile ikakhulu kwimimandla enoqoqosho olusemva.Malunga nomntu omnye kwababini kwihlabathi liphela, isifo seengcongconi sisesona soyikiso siyingozi kwimpilo yoluntu.
02 Isasazeka Njani IMalariya
1. Usulelo olusasazwa ziingcongconi
Eyona nto ithwala isifo seengcongconi yingcongconi i-Anopheles.Ixhaphake kakhulu kwiindawo ezishushu kunye ne-subtropics, kwaye izehlo zixhaphake kakhulu ehlotyeni nasekwindla kwiindawo ezininzi.
2. Ukusasazwa kwegazi
Abantu banokosulelwa sisifo seengcongconi ngokutofelwa igazi elinezifunxi-gazi zePlasmodium.Isifo seengcongconi esizalwa naso sinokubangelwa ngumonakalo kwi-placenta okanye ukosuleleka kwamanxeba omntwana ngesifo seengcongconi okanye isifo seengcongconi esithwala igazi likamama ngexesha lokubeleka.
Ukongeza, abantu abakwindawo ezingasiyo isifo seengcongconi banoxhathiso olubuthathaka kwimalariya.Isifo seengcongconi sosulela ngokulula xa izigulane okanye abathwali abasuka kwiindawo ezigqugqisayo bengena kwiindawo ezingahlaliyo.
03 Ukubonakaliswa kweklinikhi yesifo seengcongconi
Kukho iindidi ezine zePlasmodium ezenza i-parasitize emzimbeni womntu, yiPlasmodium vivax, iPlasmodium falciparum, iPlasmodium malariae kunye nePlasmodium ovale.Ezona mpawu ziphambili emva kosulelo lwemalariya ziquka ukubanda ngamaxesha athile, umkhuhlane, ukubila, njalo njalo, ngamanye amaxesha kukhatshwa yintloko, isicaphucaphu, urhudo, kunye nokukhohlela.Izigulana ezineemeko ezimandundu zisenokufumana i-delirium, isiqaqa, ukothuka, kunye nokusilela kwesibindi nezintso.Ukuba azinyangwa kwangethuba, zinokubeka ubomi esichengeni ngenxa yokulibaziseka konyango.
04 Indlela YokuThintelwa Nokulawula IMalariya
1. Usulelo lwemalariya kufuneka lunyangwe kwangethuba.Amachiza asetyenziswa kakhulu yikloroquine kunye neprimaquine.I-Artemether kunye ne-dihydroartemisinin zisebenza ngakumbi ekunyangeni isifo seengcongconi kwi-falciparum.
2. Ukongeza ekuthinteleni iziyobisi, kukwafuneka ukuba kuthathwe amanyathelo okuthintela nokuphelisa iingcongconi ukunciphisa umngcipheko wokosuleleka yimalariya kwingcambu.
3. Ukuphucula inkqubo yokufumanisa isifo seengcongconi kwaye unyange abosulelekileyo kwangethuba ukuthintela ukusasazeka kwemalariya.
05 Isisombululo
I-Macro kunye ne-Micro-Test iphuhlise uluhlu lwezixhobo zokufumanisa isifo seengcongconi, ezinokuthi zisetyenziswe kwiqonga lokufumanisa i-immunochromatography, i-fluorescent PCR iqonga lokubona kunye neqonga lokufumanisa i-isothermal amplification.Sibonelela ngezisombululo ezipheleleyo nezibanzi zoxilongo, ukujonga unyango kunye noxilongo losulelo lwePlasmodium:
I-Immunochromatography Platform
l iPlasmodium Falciparum/Plasmodium Vivax Antigen Detection Kit(Colloidal Gold)
l I-Plasmodium Falciparum ye-Antigen yokubona iKhiti (i-Colloidal Gold)
l Plasmodium Antigen Ukubonwa Kit (Colloidal Gold)
Le khithi yenzelwe ukufumanisa umgangatho we-in vitro kunye nokuchongwa kwePlasmodium falciparum (Pf), iPlasmodium vivax (Pv), iPlasmodium ovale (Po) okanye iPlasmodium malaria (Pm) kwigazi le-venous okanye igazi le-capillary labantu abaneempawu kunye neempawu ze-malaria protozoa. , enokunceda ekuxilongeni usulelo lwePlasmodium.
· Kulula ukuyisebenzisa: amanyathelo ama-3 kuphela
· Ubushushu begumbi: Ukuthutha kunye nokugcinwa kwi-4-30 ° C kwiinyanga ezingama-24
· Ukuchaneka: Uvakalelo oluphezulu kunye nokucaciswa
IQonga lePCR leFluorescent
l Ikhithi yokubona i-Plasmodium Nucleic Acid (Fluorescence PCR)
l Ikhithi yokuBonelwa kwe-Acidi yeNucleic yePlasmodium engumkhenkce (i-Fluorescence PCR)
Le khithi isetyenziselwa ukufumanisa umgangatho we-in vitro we-Plasmodium nucleic acid kwiisampulu zegazi ze-peripheral zezigulana ezinosulelo lwe-Plasmodium.
· Ulawulo lwangaphakathi: Beka iliso ngokupheleleyo kwinkqubo yovavanyo ukuqinisekisa umgangatho wovavanyo
· Ukucaciswa okuphezulu: Akukho-cross-reactivity kunye ne-pathogens yokuphefumla eqhelekileyo kwiziphumo ezichanekileyo
· Uvakalelo oluphezulu: Iikopi ezi-5/μL
I-Isothermal Amplification Platform
l Ikhithi yokufunyanwa kwe-Nucleic Acid esekwe kwi-Enzymatic Probe Isothermal Amplification (EPIA) yePlasmodium
Le khithi isetyenziselwa ukukhangela umgangatho we-in vitro we-malaria parasite nucleic acid kwiisampulu zegazi ze-peripheral zezigulana ekurhanelwa ukuba zisulelekile kwi-plasmodium.
· Ulawulo lwangaphakathi: Beka iliso ngokupheleleyo kwinkqubo yovavanyo ukuqinisekisa umgangatho wovavanyo
· Ukucaciswa okuphezulu: Akukho-cross-reactivity kunye ne-pathogens yokuphefumla eqhelekileyo kwiziphumo ezichanekileyo
· Uvakalelo oluphezulu: Iikopi ezi-5/μL
| Inombolo Yekhathalogu | Igama lemveliso | Inkcazo |
| HWTS-OT055A/B | I-Plasmodium Falciparum/Plasmodium Vivax Antigen Detection Kit(Colloidal Gold) | Uvavanyo olu-1/ikhithi, iimvavanyo ezingama-20/ikhithi |
| HWTS-OT056A/B | I-Plasmodium Falciparum ye-Antigen yokubona iKhiti (i-Colloidal Gold) | Uvavanyo olu-1/ikhithi, iimvavanyo ezingama-20/ikhithi |
| HWTS-OT057A/B | IKit yokuFumana iPlasmodium Antigen (iGolide eyiColloidal) | Uvavanyo olu-1/ikhithi, iimvavanyo ezingama-20/ikhithi |
| HWTS-OT054A/B/C | IKit yokuFumana i-Acidi yeNucleic yePlasmodium engumkhenkce (Fluorescence PCR) | Iimvavanyo ezingama-20/ikhithi, iimvavanyo ezingama-50/ikhithi, iimvavanyo ezingama-48/ikhithi |
| HWTS-OT074A/B | IKit yePlasmodium Nucleic Acid Detection(Fluorescence PCR) | Iimvavanyo ezingama-20/ikhithi, iimvavanyo ezingama-50/ikhithi |
| HWTS-OT033A/B | IKit yokuFumana i-Nucleic Acid esekwe kwi-Enzymatic Probe Isothermal Amplification (EPIA) yePlasmodium | Iimvavanyo ezingama-50/ikhithi, iimvavanyo ezili-16/ikhithi |
Ixesha lokuposa: Apr-25-2023