● I-Mycobacterium Tuberculosis
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Mycobacterium Tuberculosis Nucleic Acid and Rifampicin, Isoniazid Resistance
Le mveliso ilungele ukufunyaniswa komgangatho we-Mycobacterium tuberculosis DNA kwiisampulu zesikhohlela somntu kwi-vitro, kunye nokuguqulwa kwe-homozygous kwingingqi ye-507-533 ye-amino acid ye-codon (81bp, i-rifampicin emisela ummandla wokumelana) yejini ye-rpoB ebangela isifo sephepha seMycobacterium. ukumelana ne-rifampicin.
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I-Mycobacterium Tuberculosis ye-Isoniazid yokuNxhathisa uGuquko
Le khithi ilungele ukuchongwa okusemgangathweni kweendawo eziphambili zoguqulo kwiisampulu zesikhohlela somntu eziqokelelwe kwizigulane ezine-Tubercle bacillus positive ezikhokelela kuxhathiso lwe-mycobacterium tuberculosis isoniazid: Ingingqi ye-InhA yokukhuthaza -15C>T, -8T>A, -8T>C;Ummandla womgqugquzeli we-AhpC -12C>T, -6G>A;ukuguqulwa kwe-homozygous ye-KatG 315 codon 315G>A, 315G>C.
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I-Mycobacterium Tuberculosis Rifampicin Resistance
Le khithi ilungele ukufunyaniswa komgangatho wenguqu ye-homozygous kwingingqi ye-507-533 ye-amino acid ye-codon yejini ye-rpoB ebangela ukuxhathisa kwe-Mycobacterium tuberculosis rifampicin.
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I-Mycobacterium Tuberculosis Nucleic Acid kunye neRifampicin Resistance
Le khithi ilungele ukufunyaniswa okusemgangathweni kwe-Mycobacterium tuberculosis DNA kwiisampulu zesikhohlela somntu kwi-vitro, kunye nokuguqulwa kwe-homozygous kwindawo ye-507-533 ye-amino acid ye-codon yejini ye-rpoB ebangela ukuxhathisa kwe-Mycobacterium tuberculosis rifampicin.
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I-Mycobacterium Tuberculosis INH Ukumelana
Le kit isetyenziselwa ukufumanisa ngokusemgangathweni ukuguqulwa kwe-gene ye-315 ye-amino acid ye-katG gene (K315G> C) kunye nokuguqulwa kofuzo lommandla womgqugquzeli we-InhA gene (- 15 C> T).
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I-Mycobacterium Tuberculosis DNA
Ilungele ukufunyaniswa okusemgangathweni kwe-Mycobacterium tuberculosis DNA kwiisampulu zesikhohlela seklinikhi yabantu, kwaye ifanelekile kuxilongo oluncedisayo losulelo lwesifo sephepha seMycobacterium.
