Umkhuhlane A Virus Nucleic Acid

Intsholongwane ye-Influenza ngummeli weentlobo ze-Orthomyxoviridae.Yipathogen esongela ngokunzulu impilo yabantu.Inokosulela umamkeli kakhulu.Ubhubhani wamaxesha onyaka uchaphazela abantu abamalunga nezigidi ezingama-600 kwihlabathi jikelele kwaye ubangela ukufa kwabantu abangama-250,000 ~ 500,000, apho intsholongwane yomkhuhlane ingoyena nobangela wosulelo kunye nokufa.Intsholongwane ye-Influenza A (intsholongwane yoMkhuhlane A) yi-RNA enemisonto enye ene-negative.Ngokutsho komphezulu we-hemagglutinin (HA) kunye ne-neuraminidase (NA), i-HA inokwahlulwa ibe yi-16 subtypes, i-NA yohlulwe kwii-9 subtypes.Phakathi kweentsholongwane ze-influenza A, ii-subtypes zentsholongwane zomkhuhlane ezinokosulela ngokuthe ngqo abantu: A H1N1, H3N2, H5N1, H7N1, H7N2, H7N3, H7N7, H7N9, H9N2 kunye ne-H10N8.Phakathi kwazo, i-H1, i-H3, i-H5, kunye ne-H7 i-subtypes i-pathogenic ephezulu, kwaye i-H1N1, i-H3N2, i-H5N7, kunye ne-H7N9 ifanelwe ingqalelo ngokukhethekileyo.I-antigenicity yentsholongwane yomkhuhlane A ithanda ukuguquka, kwaye kulula ukwenza iindidi ezintsha, ezibangela ubhubhane kwihlabathi jikelele.Ukuqala ngoMatshi ka-2009, iMexico, iUnited States kunye namanye amazwe ngokulandelelana aqhambuke uhlobo olutsha lwezifo zomkhuhlane we-H1N1, kwaye ziye zasasazeka ngokukhawuleza kwihlabathi.Intsholongwane ye-Influenza A ingadluliselwa ngeendlela ezahlukeneyo ezifana ne-digestive tract, i-respiratory tract, umonakalo wolusu, kunye neliso kunye ne-conjunctiva.Iimpawu emva kosulelo ikakhulu ngumkhuhlane ophezulu, ukhohlokhohlo, impumlo evuzayo, i-myalgia, njl., uninzi lwazo lukhatshwa yinyumoniya eqatha.Intliziyo, izintso kunye nezinye iintsilelo zamalungu abantu abosuleleke kakhulu zikhokelela ekufeni, kwaye izinga lokufa liphezulu.Ke ngoko, indlela elula, echanekileyo kunye nekhawulezayo yokufumanisa umkhuhlane A intsholongwane ifuneka ngokungxamisekileyo kuqheliselo lwezonyango ukunika isikhokelo kumayeza ekliniki kunye noxilongo.