Alpha Fetoprotein(AFP) Ubungakanani

I-Alpha-fetoprotein (i-alpha fetoprotein, i-AFP) yi-glycoprotein enobunzima be-molecular malunga ne-72KD eyenziwe yi-yolk sac kunye neeseli zesibindi kwinqanaba lokuqala lophuhliso lwe-embryonic.Inomlinganiselo ophezulu wokujikeleza kwegazi lomntwana, kwaye inqanaba layo lehla liye kwisiqhelo kunyaka omnye emva kokuzalwa.Amanqanaba egazi lomntu omdala asezantsi kakhulu.Umxholo we-AFP uhambelana neqondo lokuvuvukala kunye ne-necrosis yeeseli zesibindi.Ukuphakama kwe-AFP kukubonakalisa umonakalo weseli yesibindi, i-necrosis, kunye nokunyuka okulandelayo.Ukufunyanwa kwe-Alpha-fetoprotein sisalathisi esibalulekileyo sokuxilongwa kweklinikhi kunye nokujongwa kwe-prognosis yomhlaza wesibindi osisiseko.Isetyenziswe ngokubanzi ekuxilongweni kwe-tumor kumayeza eklinikhi.

Ukuzimisela kwe-alpha-fetoprotein kungasetyenziselwa ukuxilongwa kwe-axiliary, isiphumo sokunyanga kunye nokubonwa kwe-prognosis yomhlaza wesibindi osisiseko.Kwezinye izifo (i-non-seminoma testicular umhlaza, i-neonatal hyperbilirubinemia, i-hepatitis yentsholongwane ebukhali okanye engapheliyo, i-cirrhosis yesibindi kunye nezinye izifo ezinobungozi), ukunyuka kwe-alpha-fetoprotein nako kunokubonwa, kwaye i-AFP akufanele isetyenziswe njengovavanyo lokukhangela umhlaza ngokubanzi. isixhobo.